Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556823 | 0.89 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL28689938 | 0.82 | KMT2A (0.47) | KEAP1CYP1A2SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL27943598 | 0.81 | NR5A1 (0.42) | CYP1A2CYP2C9CYP2C19KMT2ALTA4H | |
| SCHEMBL29170841 | 0.81 | NR5A1 (0.42) | CYP1A2CYP2C9CYP2C19KMT2ALTA4H | |
| SCHEMBL9641044 | 0.81 | NR5A1 (0.42) | CYP1A2CYP2C9CYP2C19KMT2ALTA4H | |
| SCHEMBL17135289 | 0.81 | NR5A1 (0.42) | CYP1A2CYP2C9CYP2C19KMT2ALTA4H | |
| SCHEMBL1556391 | 0.79 | MAPT (0.39) | KEAP1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10415469 | 0.77 | ALDH1A1 (0.38) | CYP1A2CYP2C9CYP2C19KMT2AL3MBTL1 | |
| SCHEMBL27501845 | 0.76 | CA12 (0.37) | CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL1141959 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328984-B1 | PROCESS FOR THE PREPARATON OF THIOPHENE ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-23 | — | — | EP | disclosed |
| US-4931568-A | REACTING C1-C3 ALYKYLOXYTHIOPHENES WITH ALCOHOL; MONOMERS FOR ELECTROCONDUCTIVE POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | disclosed |
| CN-1035291-A | The preparation method of thiophenethers | HOECHST AG (DE) | 1989-09-06 | — | — | CN | disclosed |
| EP-0328984-A1 | Process for the preparaton of thiophene ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |