Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454498 | 0.86 | EPHX2 (0.42) | ALDH1A1 | |
| SCHEMBL9630541 | 0.74 | CYP19A1 (0.37) | CYP19A1CNR2CNR1PTGS1PTGS2 | |
| SCHEMBL19751318 | 0.74 | KMT2A (0.34) | CYP19A1 | |
| SCHEMBL147206 | 0.74 | CYP19A1 (0.36) | CYP19A1CNR2CNR1PTGS1PTGS2 | |
| SCHEMBL11862292 | 0.70 | CRBN (0.36) | CYP19A1ALDH1A1 | |
| SCHEMBL11845960 | 0.69 | CNR2 (0.46) | CYP19A1CNR2CNR1PTGS1PTGS2 | |
| SCHEMBL11227276 | 0.68 | MGLL (0.42) | CYP19A1CNR2CNR1PTGS1PTGS2 | |
| SCHEMBL9862131 | 0.67 | MAPT (0.31) | — | |
| SCHEMBL7482405 | 0.67 | PTGS1 (0.52) | CYP19A1CNR2CNR1PTGS1PTGS2 | |
| SCHEMBL7481753 | 0.67 | PTGS1 (0.52) | CYP19A1CNR2CNR1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253553-B1 | PHOTOLYTICALLY CROSSLINKABLE THERMALLY STABLE COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 1992-10-07 | — | — | EP | claimed |
| EP-0253553-A1 | Photolytically crosslinkable thermally stable composition | THE DOW CHEMICAL COMPANY (US) | 1988-01-20 | — | — | EP | claimed |