SCHEMBL9642387

SCHEMBL9642387

CC(C)[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@H]([C]=O)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.43
▸ OPRD1 P41143 7/20 0.40
▸ OPRM1 P35372 6/20 0.40
▸ MMP2 P08253 1/20 0.40
▸ GRPR P30550 2/20 0.38
▸ OPRK1 P41145 1/20 0.38
▸ MC4R P32245 1/20 0.38
▸ PSMB1 P20618 1/20 0.38
▸ PSMB8 P28062 1/20 0.38
▸ PSMB9 P28065 1/20 0.38
▸ PSMB5 P28074 1/20 0.38
▸ PSMB10 P40306 1/20 0.38
▸ PSMB2 P49721 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389401 0.90 C5AR1 (0.48) C5AR1OPRD1OPRM1GRPR
SCHEMBL9642284 0.90 C5AR1 (0.48) C5AR1OPRD1OPRM1GRPR
SCHEMBL9749653 0.90 C5AR1 (0.48) C5AR1OPRD1OPRM1GRPR
SCHEMBL8432592 0.90 C5AR1 (0.48) C5AR1OPRD1OPRM1GRPR
SCHEMBL8436819 0.88 C5AR1 (0.46) C5AR1OPRD1OPRM1MMP2GRPR
SCHEMBL8954002 0.87 C5AR1 (0.47) C5AR1OPRD1OPRM1OPRK1
SCHEMBL9641165 0.86 SLC15A2 (0.42) C5AR1GRPRPSMB1PSMB8PSMB9
SCHEMBL29904559 0.83 C5AR1 (0.48) C5AR1MMP2
SCHEMBL677176 0.81 GLP1R (0.43) OPRD1OPRM1GRPROPRK1
SCHEMBL3125104 0.81 GLP1R (0.43) OPRD1OPRM1GRPROPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500745-A1 METAL-PEPTIDE COMPOSITIONS AND COSMETIC METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1992-09-02 — — EP disclosed
WO-1991007431-A1 METAL-PEPTIDE COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1991-05-30 — — WO disclosed
Send feedback