SCHEMBL8432592

SCHEMBL8432592

CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CCCCN)C(C)C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.48
▸ BACE1 P56817 1/20 0.43
▸ OPRM1 P35372 5/20 0.43
▸ OPRD1 P41143 5/20 0.43
▸ CTSD P07339 1/20 0.43
▸ GRPR P30550 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9642284 1.00 C5AR1 (0.48) C5AR1BACE1OPRM1OPRD1CTSD
SCHEMBL9389401 1.00 C5AR1 (0.48) C5AR1BACE1OPRM1OPRD1CTSD
SCHEMBL9749653 1.00 C5AR1 (0.48) C5AR1BACE1OPRM1OPRD1CTSD
SCHEMBL8954002 0.98 C5AR1 (0.47) C5AR1OPRM1OPRD1
SCHEMBL8436819 0.94 C5AR1 (0.46) C5AR1OPRM1OPRD1GRPR
SCHEMBL29904559 0.90 C5AR1 (0.48) C5AR1BACE1CTSD
SCHEMBL9642387 0.90 C5AR1 (0.43) C5AR1OPRM1OPRD1GRPR
SCHEMBL9751589 0.89 OPRK1 (0.45) C5AR1BACE1CTSD
SCHEMBL9751592 0.89 OPRK1 (0.45) C5AR1BACE1CTSD
SCHEMBL9389399 0.87 SLC15A2 (0.46) C5AR1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0522004-B1 USE OF COPPER(II) CONTAINING COMPOUNDS TO ACCELERATE WOUND HEALING PROCYTE CORP (US) 1999-12-15 — — EP disclosed
US-5550183-A Metal-peptide compositions and methods for stimulating hair growth PROCYTE CORPORATION (US) 1996-08-27 — — US disclosed
EP-0489860-B1 METHODS AND COMPOSITIONS FOR HEALING ULCERS PROCYTE CORP (US) 1995-08-02 — — EP disclosed
EP-0495877-B1 METHODS AND COMPOSITIONS FOR HEALING BONE PROCYTE CORP (US) 1995-03-22 — — EP disclosed
EP-0514460-A1 ANTI-OXIDATIVE AND ANTI-INFLAMMATORY METAL:PEPTIDE COMPLEXES AND USES THEREOF PROCYTE CORPORATION (US) 1992-11-25 — — EP disclosed
US-5164367-A Complexes with peptides PROCYTE CORPORATION (US) 1992-11-17 — — US disclosed
US-5145838-A Peptide derivatives PROCYTE CORPORATION (US) 1992-09-08 — — US disclosed
EP-0500745-A1 METAL-PEPTIDE COMPOSITIONS AND COSMETIC METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1992-09-02 — — EP disclosed
US-5120831-A Hair growth stimulants PROCYTE CORPORATION (US) 1992-06-09 — — US disclosed
US-5118665-A Enhance or restore resistance of mammals to damage caused by release of reactive oxygen species PROCYTE CORPORATION (US) 1992-06-02 — — US disclosed
US-5059588-A METHODS AND COMPOSITIONS FOR HEALING BONE USING GLY HIS LYS: COPPER PROCYTE CORPORATION, INCORPORATED (US) 1991-10-22 — — US disclosed
WO-1991012267-A1 ANTI-OXIDATIVE AND ANTI-INFLAMMATORY METAL:PEPTIDE COMPLEXES AND USES THEREOF PROCYTE CORPORATION (US) 1991-08-22 — — WO disclosed
US-5023237-A Using oligopeptide containing glycine, histidine, and lysine PROCYTE CORPORATION (US) 1991-06-11 — — US disclosed
WO-1991007431-A1 METAL-PEPTIDE COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH PROCYTE CORPORATION (US) 1991-05-30 — — WO disclosed
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