Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.80 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.76 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337474 | 0.90 | GRM2 (0.94) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL29466707 | 0.89 | GRM2 (1.00) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL6245198 | 0.89 | GRM2 (1.00) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL8337653 | 0.88 | GRM2 (1.00) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL3157609 | 0.82 | CYSLTR1 (0.89) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL6245754 | 0.82 | CYSLTR1 (0.83) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL6243450 | 0.81 | GRM2 (0.80) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL6246394 | 0.81 | GRM2 (1.00) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL481058 | 0.81 | CYSLTR1 (0.88) | GRM2CYSLTR1CYSLTR2 | |
| SCHEMBL3166625 | 0.81 | CYSLTR1 (0.88) | GRM2CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303478-B1 | IMPROVEMENTS IN OR RELATING TO LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| US-4820723-A | FOR TREATMENT OF HYPERSENSITIVITY, ASTHMA, SHOCK OR CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0303478-A1 | Improvements in or relating to leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1989-02-15 | — | — | EP | disclosed |