Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.31 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.31 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.31 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641640 | 1.00 | KDM4E (0.35) | KDM4EMEN1RECQLKMT2AHTT | |
| SCHEMBL9641988 | 0.91 | KDM4E (0.34) | KDM4EMEN1RECQLKMT2AHTT | |
| SCHEMBL9643118 | 0.87 | PPARG (0.36) | MEN1KMT2AHTTPPARGPPARA | |
| SCHEMBL9643144 | 0.87 | PPARG (0.36) | MEN1KMT2AHTTPPARGPPARA | |
| SCHEMBL9642345 | 0.84 | CNR1 (0.38) | KDM4EMEN1KMT2APPARGPPARA | |
| SCHEMBL9642520 | 0.83 | NFKB1 (0.33) | KDM4EMEN1RECQLKMT2AHTT | |
| SCHEMBL9642578 | 0.83 | NFKB1 (0.33) | KDM4EMEN1KMT2AHTT | |
| SCHEMBL9642526 | 0.83 | POLM (0.40) | MEN1KMT2APOLMPOLKPOLL | |
| SCHEMBL9643461 | 0.83 | CCNB2 (0.35) | KDM4E | |
| SCHEMBL9641661 | 0.83 | CCNB2 (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |