SCHEMBL9643194

SCHEMBL9643194

CC(C)(C)C(O)(Cn1cncn1)C(Cl)=CBr

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 2/20 0.44
FDPS P14324 1/20 0.42
HSP90AA1 P07900 2/20 0.40
KMT2A Q03164 1/20 0.37
CYP19A1 P11511 4/20 0.35
LMNA P02545 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
CYP2C19 P33261 1/20 0.35
ADRA1A P35348 1/20 0.35
CYP51A1 Q16850 1/20 0.35
EGLN3 Q9H6Z9 1/20 0.32
AR P10275 1/20 0.31
UGT1A4 P22310 1/20 0.31
PDE4D Q08499 1/20 0.31
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9369185 1.00 CYP3A4 (0.44) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9365397 0.87 CYP3A4 (0.45) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9365404 0.87 CYP3A4 (0.45) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9369155 0.84 FDPS (0.43) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9369161 0.84 FDPS (0.43) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9644416 0.81 CYP3A4 (0.45) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9644422 0.81 CYP3A4 (0.45) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9643648 0.80 CYP3A4 (0.47) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9788435 0.75 FDPS (0.50) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A
SCHEMBL9643270 0.74 FDPS (0.40) CYP3A4ALDH1A1FDPSHSP90AA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175169-A Preservatives or plant safening agents BAYER AKTIENGESELLSCHAFT (DE) 1992-12-29 US disclosed
US-5081140-A Fungicides, plant protection BAYER AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed