Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642908 | 1.00 | ABCB11 (0.53) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9642959 | 0.88 | ABCB11 (0.67) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9642915 | 0.85 | ABCB11 (0.49) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29371419 | 0.83 | ABCB11 (0.48) | ABCB11MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9642718 | 0.82 | ABCB11 (0.48) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9643961 | 0.81 | ABCB11 (0.57) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9642545 | 0.81 | ABCB11 (0.57) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9643876 | 0.81 | ABCB11 (0.47) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9643182 | 0.81 | ABCB11 (0.54) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9642245 | 0.81 | ABCB11 (0.54) | ABCB11MAPTLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |