Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644288 | 1.00 | RNASE1 (0.44) | RNASE1TK2TK1 | |
| SCHEMBL9644238 | 0.93 | RNASE1 (0.46) | RNASE1 | |
| SCHEMBL9644247 | 0.93 | RNASE1 (0.46) | RNASE1 | |
| SCHEMBL9644294 | 0.91 | RNASE1 (0.49) | RNASE1TK2TK1 | |
| SCHEMBL9644301 | 0.91 | RNASE1 (0.49) | RNASE1TK2TK1 | |
| SCHEMBL9644982 | 0.88 | RNASE1 (0.49) | RNASE1 | |
| SCHEMBL9644272 | 0.88 | RNASE1 (0.49) | RNASE1 | |
| SCHEMBL9644348 | 0.87 | TK2 (0.53) | TK2TK1 | |
| SCHEMBL9644358 | 0.87 | TK2 (0.53) | TK2TK1 | |
| SCHEMBL9645091 | 0.87 | RNASE1 (0.50) | RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255894-B1 | PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-07 | — | — | EP | claimed |
| US-4882316-A | CONTROL AND PREVENTION OF VIRAL INFECTIONS | HOFFMANN-LA ROCHE INC. (US) | 1989-11-21 | — | — | US | disclosed |