SCHEMBL9644341

SCHEMBL9644341

CCCc1c(C(=O)O)cccc1-c1ccc(CC)cc1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.49
LTB4R2 Q9NPC1 3/20 0.46
AGTR1 P30556 1/20 0.45
AGTR2 P50052 1/20 0.45
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23512487 0.83 SMN1; SMN2 (0.50) PPARGLTB4R2AGTR1
SCHEMBL7730341 0.82 RARB (0.45) PPARGLTB4R2MCL1
SCHEMBL8676465 0.82 LTB4R2 (0.50) PPARGLTB4R2
SCHEMBL202160 0.81 LTB4R2 (0.61) PPARGLTB4R2AGTR1
SCHEMBL10536375 0.81 RARB (0.59) LTB4R2
SCHEMBL7722704 0.81 MCL1 (0.52) PPARGLTB4R2AGTR1MCL1
SCHEMBL25146615 0.81 MCL1 (0.52) PPARGLTB4R2AGTR1MCL1
SCHEMBL10535282 0.79 CLCN2 (0.48) LTB4R2
SCHEMBL28897092 0.79 LTB4R2 (0.52) PPARGLTB4R2AGTR1
SCHEMBL3391070 0.79 ALDH1A1 (0.48) MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130828-A Liquid crystal temperature sensor and materials MANCHESTER R&D PARTNERSHIP (US) 1992-07-14 US disclosed
US-4884877-A Liquid crystal temperature sensor and materials utilizing microencapsulated liquid crystal MANCHESTER R & D PARTNERSHIP (US) 1989-12-05 US disclosed
EP-0187768-A4 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. FERGASON JAMES L 1989-03-09 EP disclosed
EP-0187768-A1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. FERGASON JAMES L 1986-07-23 EP disclosed
WO-1985005467-A1 LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS FERGASON JAMES L 1985-12-05 WO disclosed