Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964449 | 1.00 | NPC1 (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2GLS | |
| SCHEMBL964008 | 0.81 | ALDH1A1 (0.34) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL964006 | 0.81 | ALDH1A1 (0.34) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL965897 | 0.79 | ALDH1A1 (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2GLS | |
| SCHEMBL965896 | 0.79 | ALDH1A1 (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2GLS | |
| SCHEMBL963207 | 0.79 | PHGDH (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL963205 | 0.79 | PHGDH (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL963496 | 0.78 | HTT (0.47) | ALDH1A1RAB9ASMN1; SMN2GLSHTT | |
| SCHEMBL964447 | 0.77 | NPC1 (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2ELANE | |
| SCHEMBL962750 | 0.76 | ATM (0.39) | ALDH1A1KDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | PPARA, PPARD, PPARG | NPC1 1538/4885ALDH1A1 821/4885RAB9A 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.