SCHEMBL9644544

SCHEMBL9644544

C/C(=C\Cl)c1cccc(Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
CTSA P10619 3/20 0.34
HTR3E A5X5Y0 2/20 0.33
HTR3B O95264 2/20 0.33
HTR3A P46098 2/20 0.33
HTR3D Q70Z44 2/20 0.33
HTR3C Q8WXA8 2/20 0.33
GAA P10253 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 2/20 0.31
ALOX15 P16050 1/20 0.31
ACMSD Q8TDX5 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
AGTR1 P30556 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9644550 1.00 ALDH1A1 (0.40) ALDH1A1TSHRCYP3A4CTSAHTR3E
SCHEMBL10395613 0.76 CTSA (0.36) CTSAGAAKDM4E
SCHEMBL10395614 0.76 CTSA (0.36) CTSAGAAKDM4E
SCHEMBL13130698 0.75 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4CTSAHTR3E
SCHEMBL29426968 0.75 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4CTSAHTR3E
SCHEMBL29793731 0.75 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4CTSAGAA
SCHEMBL3363179 0.75 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4CTSAGAA
SCHEMBL9368741 0.75 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4CTSAHTR3E
SCHEMBL18021075 0.72 ALDH1A1 (0.40) ALDH1A1TSHRCYP3A4CTSAHTR3E
SCHEMBL28210699 0.70 TSHR (0.46) ALDH1A1TSHRCYP3A4CTSAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5123953-A DIHALOGENATED HERBICIDAL SULPHONES RHONE-POULENC AGROCHIMIE (FR) 1992-06-23 US disclosed