Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.34 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644956 | 1.00 | CTDSP1 (0.40) | CTDSP1FAPPTGS1ABCB11PDE4D | |
| SCHEMBL10638997 | 0.91 | NR1I2 (0.43) | CTDSP1FAPPTGS1NR1I2PPARG | |
| SCHEMBL10639008 | 0.91 | NR1I2 (0.43) | CTDSP1FAPPTGS1NR1I2PPARG | |
| SCHEMBL9643776 | 0.89 | CTDSP1 (0.47) | CTDSP1PTGS1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL5712680 | 0.86 | PTGS1 (0.43) | CTDSP1PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL5712682 | 0.86 | PTGS1 (0.43) | CTDSP1PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL10516494 | 0.86 | PTGS1 (0.43) | CTDSP1PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL9201934 | 0.86 | NR1I2 (0.47) | CTDSP1FAPPTGS1ABCB11PDE4D | |
| SCHEMBL10516499 | 0.86 | PTGS1 (0.43) | CTDSP1PTGS1ABCB11PDE4DNR1I2 | |
| SCHEMBL9622714 | 0.86 | PTGS1 (0.43) | CTDSP1PTGS1ABCB11PDE4DNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168327-B1 | CEPHALOSPORIN COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4791197-A | ANTIBIOTICS | SAKAGAMI KENJI (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0168327-A2 | Cephalosporin compounds | MEIJI SEIKA KAISHA LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |