Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712680 | 1.00 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10985834 | 0.95 | PTGS1 (0.44) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10985827 | 0.95 | PTGS1 (0.44) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10636340 | 0.95 | PTGS1 (0.44) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9196828 | 0.95 | PTGS1 (0.44) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9827358 | 0.92 | PTGS1 (0.45) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9204591 | 0.92 | PTGS1 (0.45) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9413830 | 0.92 | NR1I2 (0.51) | PTGS1NR1I2HTR2CPPARGESR1 | |
| SCHEMBL9413831 | 0.92 | NR1I2 (0.51) | PTGS1NR1I2HTR2CPPARGESR1 | |
| SCHEMBL10516499 | 0.91 | PTGS1 (0.43) | PTGS1ABCB11PDE4DNR1I2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325923-B1 | CEPHEM COMPOUNDS AND ESBL-DETECTING REAGENTS CONTAINING THE SAME | ZENYAKU KOGYO KK (JP) | 2006-12-06 | — | — | EP | disclosed |
| US-6897304-B2 | Cephem compounds and ESBL-detecting reagents containing the same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2005-05-24 | — | — | US | disclosed |
| US-20040019202-A1 | Cephem compounds and esbl-detecting reagents containing the same | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-01-29 | — | — | US | disclosed |
| EP-1325923-A1 | CEPHEM COMPOUNDS AND ESBL-DETECTING REAGENTS CONTAINING THE SAME | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019202-A1 | Cephem compounds and esbl-detecting reagents containing the same | MRPL21, CLIC1, QSOX1 | PTGS1 2523/4885ABCB11 282/4885PDE4D 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.