Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523174 | 0.88 | ALDH1A1 (0.67) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL9647951 | 0.86 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10353821 | 0.82 | TSHR (0.70) | ALDH1A1L3MBTL1LMNANPC1TSHR | |
| SCHEMBL2289848 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GAASMN1; SMN2RAB9ANPC1 | |
| Furan SCHEMBL28237984 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL11521670 | 0.79 | TSHR (0.78) | ALDH1A1L3MBTL1LMNATSHRMAPT | |
| SCHEMBL29448827 | 0.79 | GAA (0.65) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL27323869 | 0.79 | GAA (0.65) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL2707041 | 0.79 | ALDH1A1 (0.56) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL1928460 | 0.79 | ALDH1A1 (0.68) | ALDH1A1GAASMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |