Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710460 | 1.00 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28924377 | 1.00 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3193637 | 1.00 | TSHR (0.69) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9136472 | 0.98 | TSHR (0.67) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8651324 | 0.98 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9001839 | 0.94 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1931997 | 0.92 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| Methacrylic Acid SCHEMBL9136483 | 0.90 | TSHR (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554413 | 0.89 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22023212 | 0.89 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505406-A1 | PROCESS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009005-A1 | PROCESS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |