Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879068 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL8993857 | 0.79 | AKR1C3 (0.50) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL1070872 | 0.79 | AKR1C3 (0.55) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL13715317 | 0.78 | MEN1 (0.51) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL15969887 | 0.78 | AKR1C3 (0.48) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL28611640 | 0.78 | MAPT (0.58) | AKR1C3AKR1C1MEN1KMT2AMAPT | |
| SCHEMBL15052966 | 0.78 | AKR1C3 (0.48) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL14130850 | 0.78 | AKR1C3 (0.48) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL8303279 | 0.77 | AKR1C3 (0.44) | AKR1C3AKR1C1CYP3A4CYP2C9MEN1 | |
| SCHEMBL388143 | 0.76 | AKR1C3 (0.57) | AKR1C3AKR1C1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379911-B1 | N-PHENYL TETRAHYDROINDAZOLE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-12-02 | — | — | EP | claimed |
| US-4990174-A | N-phenyltetrahydroindazole derivatives herbicidal compositions and use | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |