SCHEMBL388143

SCHEMBL388143

CC(=O)NC(=Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.57
ALDH1A1 P00352 3/20 0.52
TSHR P16473 1/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
RECQL P46063 1/20 0.49
MTNR1A P48039 2/20 0.47
MTNR1B P49286 2/20 0.47
HTT P42858 1/20 0.47
GLA P06280 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
AKR1C1 Q04828 1/20 0.46
RAB9A P51151 3/20 0.45
MAPT P10636 2/20 0.45
NPC1 O15118 2/20 0.44
POLB P06746 1/20 0.44
FBP1 P09467 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388142 1.00 AKR1C3 (0.57) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL786716 1.00 AKR1C3 (0.57) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL387760 0.98 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRMEN1KMT2A
Methyl Alcohol SCHEMBL8740650 0.98 AKR1C3 (0.55) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL15085946 0.90 TP53 (0.56) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL5498513 0.89 MEN1 (0.46) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL12561790 0.89 RECQL (0.53) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL27415288 0.85 RAB9A (0.50) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL10739476 0.85 ALDH1A1 (0.52) AKR1C3ALDH1A1TSHRMEN1KMT2A
SCHEMBL10739481 0.85 ALDH1A1 (0.52) AKR1C3ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 436 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119638312-A High-performance solid waste-based grouting material and preparation method thereof 太行城乡建设集团有限公司 2025-03-18 CN claimed
CN-119176708-A Method for preparing ceramsite adsorption material by coupling gasified slag with biochar 伊犁师范大学 2024-12-24 CN claimed
CN-118852528-A Ultralow-viscosity grouting material suitable for coal mine powdery coal body roadway difficult to penetrate and preparation method thereof 中煤科工开采研究院有限公司 2024-10-29 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-114667823-B Method for accelerating germination of tomato seeds by using magnetic field 安徽省富美四季农业科技有限公司 2024-02-09 CN claimed
CN-115785067-A Preparation method of impurity compound of esomeprazole thioether 北京京卫燕康药物研究所有限公司 2023-03-14 CN claimed
CN-114667823-A Method for accelerating germination of tomato seeds by using magnetic field 安徽省富美四季农业科技有限公司 2022-06-28 CN claimed
WO-2018204829-A1 METHODS FOR PREVENTING NEURAL TUBE DEFECTS IN DIABETIC PREGNANCY UNIVERSITY OF MARYLAND, BALTIMORE (US) 2018-11-08 WO claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-5510503-A Bisphosphines for asymmetric hydrogenation catalysts BAYER AKTIENGESELLSCHAFT (DE) 1996-04-23 US claimed
US-5510507-A COORDINATION CATALYSTS; EFFICIENT ENANTIOSELECTIVITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-23 US claimed
WO-1995018787-A1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-13 WO claimed
US-5099077-A Dihydrocarbylphosphioxy substituted groups with amine or phosphinoamines as ligands SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) 1992-03-24 US claimed
EP-0252216-B1 MICROBIOLOGICALLY PRODUCED ALPHA-ACETYLAMINO CINNAMIC ACID ACYLASE, METHOD OF ITS PRODUCTION AND ITS USE Degussa Aktiengesellschaft (DE) 1992-01-29 EP claimed
US-4795816-A 2-methyl-4-benzyl-5-oxazolidinone THE DOW CHEMICAL COMPANY (US) 1989-01-03 US claimed
EP-0210210-B1 METHOD FOR PRODUCING L-PHENYLALANINE NORSOLOR S.A. (FR) 1988-11-23 EP claimed
EP-0212972-A2 Bioconversion process ALLELIX INC. (CA) 1987-03-04 EP claimed
EP-0077099-A2 Process for preparing amino acids and their esters ANIC S.p.A. (IT) 1983-04-20 EP claimed
US-4328364-A RHODIUM CATALYST SNAMPROGETTI, S.P.A. (IT) 1982-05-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS AKR1C3 4367/4885ALDH1A1 3087/4885TSHR 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.