Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644476 | 0.83 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9645657 | 0.82 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9645387 | 0.80 | ALOX5 (0.72) | ALOX5 | |
| SCHEMBL9645270 | 0.79 | ALOX5 (0.71) | ALOX5 | |
| SCHEMBL9645399 | 0.77 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9645210 | 0.76 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL10511852 | 0.75 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL9645808 | 0.75 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL9644521 | 0.74 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL1274602 | 0.74 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |