Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.86 |
| ▸ | RAB9A | P51151 | 4/20 | 0.86 |
| ▸ | NPC1 | O15118 | 3/20 | 0.86 |
| ▸ | GAA | P10253 | 3/20 | 0.86 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724997 | 0.93 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1GAAPTPN1 | |
| SCHEMBL10939388 | 0.91 | SMN1; SMN2 (0.91) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL10943445 | 0.89 | RAB9A (0.88) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL5879030 | 0.89 | RAB9A (0.88) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL24106782 | 0.86 | MEN1 (0.70) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL570961 | 0.86 | MEN1 (0.70) | SMN1; SMN2RAB9ANPC1GAAMEN1 | |
| SCHEMBL3209227 | 0.86 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1GAAPTPN1 | |
| SCHEMBL22223650 | 0.85 | PTPN1 (0.94) | SMN1; SMN2RAB9ANPC1PTPN1MEN1 | |
| SCHEMBL2835618 | 0.85 | PTPN1 (0.94) | SMN1; SMN2RAB9ANPC1PTPN1MEN1 | |
| SCHEMBL29611669 | 0.85 | PTPN1 (0.94) | SMN1; SMN2RAB9ANPC1PTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346713-B1 | BENZAMIDINES USEFUL AS ULTRAVIOLET LIGHT ABSORBERS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-5011628-A | N,N'-diarylbenzamidines useful as ultraviolet light absorbers | GIVAUDAN CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |