Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645788 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9645423 | 0.99 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9644606 | 0.94 | RAB9A (0.68) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9644601 | 0.94 | RAB9A (0.68) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9645282 | 0.92 | RAB9A (0.67) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9645292 | 0.92 | RAB9A (0.67) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9654865 | 0.87 | RAB9A (0.58) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9654859 | 0.87 | RAB9A (0.58) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9645843 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 | |
| SCHEMBL9645842 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AGAANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346713-B1 | BENZAMIDINES USEFUL AS ULTRAVIOLET LIGHT ABSORBERS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-5011628-A | N,N'-diarylbenzamidines useful as ultraviolet light absorbers | GIVAUDAN CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0346713-A1 | Benzamidines useful as ultraviolet light absorbers | L. GIVAUDAN & CIE Société Anonyme (CH) | 1989-12-20 | — | — | EP | disclosed |