SCHEMBL9645878

SCHEMBL9645878

CCCCCCCCCCCCCCC(CCCCCCCCCCCCCCOCC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.53
GRIK2 Q13002 2/20 0.53
CA2 P00918 2/20 0.50
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
MAPK1 P28482 1/20 0.50
GPR84 Q9NQS5 3/20 0.48
FFAR1 O14842 1/20 0.48
CES2 O00748 2/20 0.47
MAPT P10636 1/20 0.47
LCK P06239 1/20 0.47
PPARD Q03181 1/20 0.47
ZDHHC20 Q5W0Z9 1/20 0.47
ZDHHC2 Q9UIJ5 1/20 0.47
CHRM1 P11229 1/20 0.47
AKR1A1 P14550 1/20 0.47
CHRM3 P20309 1/20 0.47
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
ADRA1A P35348 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771201 1.00 GRIK1 (0.53) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL30839915 1.00 GRIK1 (0.53) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL11068865 1.00 GRIK1 (0.53) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL5357202 0.96 CA2 (0.55) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL5356502 0.96 CA2 (0.55) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL5361363 0.96 CA2 (0.55) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL2356532 0.95 CA2 (0.57) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL28633774 0.93 GRIK1 (0.53) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL8331529 0.93 GRIK1 (0.56) GRIK1GRIK2CA2SLC1A2SLC1A1
SCHEMBL28490749 0.93 GRIK1 (0.56) GRIK1GRIK2CA2SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0283165-B1 SKIN CONDITIONING COMPOSITION AND METHOD THE PROCTER & GAMBLE COMPANY (US) 1992-10-28 EP disclosed
US-4976953-A WITH NONGREASY, NONTACKY FEEL THE PROCTER & GAMBLE COMPANY (US) 1990-12-11 US disclosed
US-4806262-A SURFACTANTS AND MOISTURIZER; NO RINSING THE PROCTER & GAMBLE COMPANY (US) 1989-02-21 US disclosed
EP-0283165-A2 Skin conditioning composition and method THE PROCTER & GAMBLE COMPANY (US) 1988-09-21 EP disclosed
US-4708813-A NONIONIC SURFACTANT, FATTY ALCOHOL, EMOLLIENT, SKIN MOISTURIZER, WATER THE PROCTER & GAMBLE COMPANY (US) 1987-11-24 US disclosed
EP-0213827-A2 Nonfoaming cleansing mousse with skin conditioning benefits THE PROCTER & GAMBLE COMPANY (US) 1987-03-11 EP disclosed