Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490 | 0.87 | — | — | |
| SCHEMBL10649555 | 0.87 | — | — | |
| SCHEMBL28645784 | 0.80 | — | — | |
| SCHEMBL31367011 | 0.80 | — | — | |
| SCHEMBL10416943 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL8051087 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL662589 | 0.80 | — | — | |
| SCHEMBL5495232 | 0.80 | — | — | |
| SCHEMBL116471 | 0.80 | — | — | |
| SCHEMBL17698517 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331312-B1 | PROCESS FOR PREPARING ELASTOMERIC POLYARYLATE GRAFT COPOLYMERS AND POLYARYLATE BEARING ONE DIHYDROCYCLOBUTENE END GROUP | AMOCO CORPORATION (US) | 1992-11-11 | — | — | EP | disclosed |
| US-4937287-A | Addition-condensation copolymers; oxidation and heat resistance, photostability | AMOCO CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |