Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 1.00 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800928 | 0.79 | KDM4E (0.65) | KDM4EKMT2AALDH1A1PSMD14COPS5 | |
| SCHEMBL26964191 | 0.79 | KDM4E (0.65) | KDM4EKMT2AALDH1A1PSMD14COPS5 | |
| SCHEMBL1787225 | 0.78 | KDM4E (1.00) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| SCHEMBL23954391 | 0.77 | KDM4E (0.63) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| Jineol SCHEMBL4213727 | 0.77 | KDM4E (0.67) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| Jineol SCHEMBL29696064 | 0.77 | KDM4E (0.67) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| Hydrochloric Acid SCHEMBL9333864 | 0.76 | KDM4E (0.96) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| SCHEMBL27824094 | 0.76 | KDM4E (0.96) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| Jineol SCHEMBL28133873 | 0.76 | KDM4E (0.65) | KDM4EMETAP2TSHRMMP2CHRM1 | |
| SCHEMBL14046290 | 0.74 | KDM4E (0.62) | KDM4EMETAP2TSHRMMP2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202111-B1 | ANTIBACTERIAL MYCAMINOSYL TYLONOLIDE DERIVATIVES AND THEIR PRODUCTION | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-09-13 | — | — | EP | claimed |
| EP-0202111-A1 | Antibacterial mycaminosyl tylonolide derivatives and their production | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1986-11-20 | — | — | EP | claimed |
| US-5101022-A | Macrolactone Antibiotics | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4945081-A | Antibiotic, bactericide | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| US-4914192-A | ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0202111-B1 | ANTIBACTERIAL MYCAMINOSYL TYLONOLIDE DERIVATIVES AND THEIR PRODUCTION | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4794173-A | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0202111-A1 | Antibacterial mycaminosyl tylonolide derivatives and their production | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1986-11-20 | — | — | EP | disclosed |