Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 11/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.56 |
| ▸ | HTR3B | O95264 | 6/20 | 0.56 |
| ▸ | HTR3A | P46098 | 6/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9645586 | 0.99 | ALDH1A1 (0.61) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL9731274 | 0.90 | CHRNA7 (0.55) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL2824521 | 0.86 | CHRM2 (0.53) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL4199079 | 0.84 | ALDH1A1 (0.61) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL4204798 | 0.84 | ALDH1A1 (0.61) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL7060353 | 0.81 | ALDH1A1 (0.69) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A | |
| SCHEMBL7180545 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CHRNA7HTR3A | |
| SCHEMBL11920206 | 0.79 | CHRNA7 (0.64) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL2897511 | 0.79 | CHRNA7 (0.63) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7063259 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CHRNA7HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327335-B1 | ARYLAMIDO(AND ARYLTHIOAMIDO)-AZABICYCLOALKANES FOR ENHANCING MEMORY OR CORRECTING MEMORY DEFICIENCY | SYNTHELABO (FR) | 1992-10-14 | — | — | EP | claimed |
| EP-0190920-A2 | Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)azabicycloalkanes | SYNTHELABO (FR) | 1986-08-13 | — | — | EP | claimed |
| EP-0327335-B1 | ARYLAMIDO(AND ARYLTHIOAMIDO)-AZABICYCLOALKANES FOR ENHANCING MEMORY OR CORRECTING MEMORY DEFICIENCY | SYNTHELABO (FR) | 1992-10-14 | — | — | EP | disclosed |