Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648524 | 1.00 | S1PR5 (0.41) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9646227 | 1.00 | S1PR5 (0.41) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9646244 | 1.00 | S1PR5 (0.41) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9648515 | 1.00 | S1PR5 (0.41) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9648505 | 1.00 | S1PR5 (0.41) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9855784 | 0.99 | S1PR5 (0.43) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9647914 | 0.99 | KMT2A (0.40) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9647908 | 0.99 | KMT2A (0.40) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9647905 | 0.99 | KMT2A (0.40) | S1PR5SMN1; SMN2TP53TSHRNFKB1 | |
| SCHEMBL9646731 | 0.98 | S1PR5 (0.40) | S1PR5SMN1; SMN2TP53TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108652-A | Liquid crystal dielectrics | Merck patent Gesellschaft mit beschrankter Haftung Darmstadt (DE) | 1992-04-28 | — | — | US | disclosed |
| US-4986931-A | Cyclohexane derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4510069-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-09 | — | — | US | disclosed |