Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646244 | 0.99 | S1PR5 (0.41) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9648515 | 0.99 | S1PR5 (0.41) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9646227 | 0.99 | S1PR5 (0.41) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9646236 | 0.99 | S1PR5 (0.41) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9648505 | 0.99 | S1PR5 (0.41) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9648524 | 0.99 | S1PR5 (0.41) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9647914 | 0.98 | KMT2A (0.40) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9647908 | 0.98 | KMT2A (0.40) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9647905 | 0.98 | KMT2A (0.40) | S1PR5TP53TSHRNFKB1NFKB2 | |
| SCHEMBL9856223 | 0.97 | RARB (0.46) | S1PR5TP53TSHRNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075032-A | Electrooptics, switches, displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-12-24 | — | — | US | disclosed |
| US-4886620-A | Smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-12-12 | — | — | US | disclosed |