Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646327 | 0.73 | BRD4 (0.31) | BRD4 | |
| SCHEMBL9646337 | 0.69 | PARP1 (0.44) | PARP1USP30MEN1TSHRKMT2A | |
| SCHEMBL3507808 | 0.66 | BRD4 (0.53) | NPSR1RAB9ABRD4POLBNR4A1 | |
| SCHEMBL31667300 | 0.65 | CHRM2 (0.43) | PARP1BRD4 | |
| SCHEMBL9646454 | 0.65 | CHRM2 (0.43) | PARP1BRD4 | |
| SCHEMBL18764530 | 0.65 | PARP1 (0.51) | PARP1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL14384831 | 0.64 | NPSR1 (0.64) | PARP1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL7425747 | 0.64 | AURKA (0.48) | PARP1USP30TSHR | |
| SCHEMBL9647856 | 0.64 | PARP1 (0.53) | PARP1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL9647852 | 0.64 | PARP1 (0.49) | PARP1MEN1TSHRKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |