Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646352 | 0.83 | NR1H2 (0.40) | PARP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL9647155 | 0.80 | KMT2A (0.53) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL31667524 | 0.77 | P2RX4 (0.49) | MEN1KMT2ATP53 | |
| SCHEMBL31667699 | 0.71 | POLB (0.48) | MEN1KMT2ATP53 | |
| SCHEMBL9647856 | 0.70 | PARP1 (0.53) | PARP1MEN1TSHRKMT2AERCC5 | |
| SCHEMBL3507808 | 0.70 | BRD4 (0.53) | NPSR1RAB9ABRD4USP2SENP5 | |
| SCHEMBL9646334 | 0.69 | PARP1 (0.42) | PARP1MEN1TSHRKMT2AERCC5 | |
| SCHEMBL9670940 | 0.67 | L3MBTL1 (0.65) | MEN1KMT2ABRD4 | |
| SCHEMBL9647043 | 0.67 | GAA (0.44) | MEN1TSHRKMT2AMAPTNPSR1 | |
| SCHEMBL8388917 | 0.67 | NPSR1 (0.50) | PARP1MEN1TSHRKMT2AERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |