Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121751 | 0.77 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL31121749 | 0.77 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL2239345 | 0.75 | CTSK (0.52) | CTSKCTSS | |
| SCHEMBL22661716 | 0.75 | CTSK (0.52) | CTSKCTSS | |
| SCHEMBL28012265 | 0.75 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL24465592 | 0.75 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL24739376 | 0.75 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL18205407 | 0.75 | CTSK (0.52) | CTSKCTSS | |
| SCHEMBL28398590 | 0.75 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL14820491 | 0.75 | CTSK (0.59) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |