Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 10/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647128 | 1.00 | DPEP1 (0.63) | DPEP1GRIK1GRIK2METAP1GRIN2D | |
| SCHEMBL9647139 | 1.00 | DPEP1 (0.63) | DPEP1GRIK1GRIK2METAP1GRIN2D | |
| SCHEMBL9645166 | 0.84 | DPEP1 (0.63) | DPEP1GRIK1METAP1GRIN2DGRIN3B | |
| SCHEMBL9646018 | 0.84 | DPEP1 (0.63) | DPEP1GRIK1METAP1GRIN2DGRIN3B | |
| SCHEMBL9647109 | 0.84 | DPEP1 (0.63) | DPEP1GRIK1METAP1GRIN2DGRIN3B | |
| SCHEMBL9646250 | 0.80 | GRIK1 (0.47) | DPEP1GRIK1GRIK2 | |
| SCHEMBL9646228 | 0.80 | GRIK1 (0.47) | DPEP1GRIK1GRIK2 | |
| SCHEMBL9244392 | 0.79 | GRIK1 (0.50) | DPEP1GRIK1GRIK2 | |
| SCHEMBL9245892 | 0.79 | GRIK1 (0.50) | DPEP1GRIK1GRIK2 | |
| SCHEMBL9245717 | 0.79 | GRIK1 (0.50) | DPEP1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | claimed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |