⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL27601177 | 0.73 | TSHR (0.64) | — | |
| SCHEMBL22012075 | 0.73 | — | — | |
| SCHEMBL3076182 | 0.71 | — | — | |
| SCHEMBL3076180 | 0.71 | — | — | |
| SCHEMBL5610740 | 0.71 | — | — | |
| SCHEMBL20961907 | 0.69 | — | — | |
| SCHEMBL22074463 | 0.69 | — | — | |
| SCHEMBL3068136 | 0.69 | — | — | |
| Maleic Acid SCHEMBL15660586 | 0.68 | TSHR (0.82) | — | |
| Maleic Acid SCHEMBL1924596 | 0.68 | TSHR (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247577-B2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2022-04-27 | — | — | EP | disclosed |
| US-8629288-B2 | Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| EP-2671873-A1 | Method for the cyclization of hydrazinoacrylic acid derivatives | SOLVAY SA (BE) | 2013-12-11 | — | — | EP | disclosed |
| EP-2671873-A1 | Method for the cyclization of hydrazinoacrylic acid derivatives | SOLVAY SA (BE) | 2013-12-11 | — | — | EP | disclosed |
| US-8592605-B2 | Method for the regioselective synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20130197239-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-Haloalkyl-Pyrazole-4-Carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20110009642-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | disclosed |
| EP-1754994-B1 | Process for the preparation of an anti-reflection film | FUJIFILM CORP (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1754994-A1 | Process for the preparation of an anti-reflection film | FUJI PHOTO FILM CO., LTD. (JP) | 2007-02-21 | — | — | EP | disclosed |
| US-7108810-B2 | Anti-reflection film and process for the preparation of the same | FUJI PHOTO FILM CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20030077437-A1 | Anti-reflection film and process for the preparation of the same | FUJIFILM CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-0989443-A2 | Anti-reflection film and process for the preparation of the same | FUJI PHOTO FILM CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |