Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237566 | 0.84 | CYP1A2 (0.44) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL3433496 | 0.83 | GSK3B (0.43) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL31678819 | 0.83 | GSK3B (0.43) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL3403968 | 0.81 | CTSA (0.45) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL15019936 | 0.80 | KDM4E (0.44) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL24443478 | 0.80 | CTSA (0.44) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL29689811 | 0.80 | CTSA (0.44) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL8866132 | 0.80 | CTSA (0.45) | CTSAKDM4EMEN1KMT2AGAA | |
| SCHEMBL6578005 | 0.79 | CYP1A2 (0.55) | KDM4EMEN1KMT2AGAACYP1A2 | |
| SCHEMBL9364903 | 0.79 | CTSA (0.38) | CTSAKDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-4863939-A | Heteroarylethylamine as production promoters in livestock | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0256420-A2 | Heteroarylethyl amines, process for their synthesis and their use in the promotion of animal performance | BAYER AG (DE) | 1988-02-24 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |