SCHEMBL9364903

SCHEMBL9364903

C=C(CCl)c1cccc(OC)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.38
APLNR P35414 1/20 0.34
HTR1A P08908 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
DRD3 P35462 1/20 0.34
TAS2R8 Q9NYW2 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GAA P10253 1/20 0.34
MTNR1A P48039 6/20 0.34
MTNR1B P49286 6/20 0.34
BTK Q06187 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8865629 0.80 CTSA (0.39) CTSAAPLNRKDM4EMEN1KMT2A
SCHEMBL9648449 0.79 CTSA (0.43) CTSAAPLNRHTR1AHTR2AHTR2C
SCHEMBL9365129 0.78 ALDH1A1 (0.42) CTSAHTR1AHTR2AKDM4E
SCHEMBL9364919 0.78 CTSA (0.38) CTSAAPLNRKDM4EMEN1KMT2A
SCHEMBL9370170 0.77 P2RX7 (0.49) CTSAMEN1KMT2AMAPT
SCHEMBL9365021 0.74 ALDH1A1 (0.41) CTSAKDM4EGAACYP3A4MAPT
SCHEMBL15019936 0.73 KDM4E (0.44) CTSAAPLNRTAS2R8KDM4EMEN1
SCHEMBL9365832 0.72 P2RX7 (0.31)
SCHEMBL31589777 0.72 APLNR (0.51) CTSAAPLNRHTR1AHTR2AHTR2C
SCHEMBL8866132 0.72 CTSA (0.45) CTSAAPLNRKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281110-B1 N-[2-(pyridyl)propyl]-N-substituted sulfonamide, herbicide containing the same as an active ingredient and intermediate thereof MITSUBISHI CHEM IND (JP) 1994-09-07 EP disclosed
US-4960897-A Herbicide containing 1-(halogenomethyl)-vinyl pyridines MITSUBISHI KASEI CORPORATION (JP) 1990-10-02 US disclosed
EP-0281110-A2 N-[2-(pyridyl)propyl]-N-substituted sulfonamide, herbicide containing the same as an active ingredient and intermediate thereof MITSUBISHI KASEI CORPORATION (JP) 1988-09-07 EP disclosed