Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172037 | 0.80 | MAPT (0.47) | MAPTNAAAHPGDCES2 | |
| SCHEMBL28651451 | 0.73 | CSNK1E (0.41) | MAPTNAAALMNAPOLB | |
| SCHEMBL2999572 | 0.72 | CES2 (0.64) | CES2 | |
| SCHEMBL999330 | 0.71 | CES2 (0.53) | LMNACES2 | |
| SCHEMBL28144251 | 0.71 | ASAH1 (0.52) | NAAACES2 | |
| Octane SCHEMBL28263947 | 0.70 | MAPT (0.47) | MAPTNAAALMNAPOLBHPGD | |
| Hexanoate SCHEMBL28004389 | 0.69 | AKR1B1 (0.50) | MAPT | |
| SCHEMBL2167814 | 0.69 | ASAH1 (0.63) | NAAACES2 | |
| SCHEMBL10707151 | 0.69 | ASAH1 (0.47) | NAAACES2 | |
| SCHEMBL7143109 | 0.69 | HPGD (0.46) | MAPTNAAALMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | claimed |