Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649437 | 1.00 | DRD2 (0.51) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9649282 | 0.96 | DRD2 (0.50) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9649275 | 0.96 | DRD2 (0.50) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9646881 | 0.94 | DRD2 (0.49) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9646302 | 0.94 | DRD2 (0.49) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9646296 | 0.94 | DRD2 (0.49) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9646888 | 0.94 | DRD2 (0.49) | DRD2ALDH1A1GAAHSD17B10MEN1 | |
| SCHEMBL9648294 | 0.91 | DRD2 (0.54) | DRD2ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL9648301 | 0.91 | DRD2 (0.54) | DRD2ALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL9648560 | 0.87 | S1PR3 (0.43) | DRD2MEN1KMT2AS1PR3ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107759-B1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS COMPONENTS FOR LIQUID CRYSTALS | MERCK PATENT GmbH (DE) | 1992-12-16 | — | — | EP | disclosed |
| US-5108652-A | Liquid crystal dielectrics | Merck patent Gesellschaft mit beschrankter Haftung Darmstadt (DE) | 1992-04-28 | — | — | US | disclosed |
| US-4986931-A | Cyclohexane derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4510069-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-09 | — | — | US | disclosed |