Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739896 | 0.82 | KMT2A (0.41) | KMT2ANOTUMLMNAALDH1A1EPHX2 | |
| SCHEMBL8068071 | 0.81 | KMT2A (0.37) | KMT2ANOTUMLMNAALDH1A1EPHX2 | |
| SCHEMBL11733894 | 0.76 | KMT2A (0.42) | KMT2ALMNAALDH1A1MEN1RAB9A | |
| SCHEMBL8077395 | 0.75 | KMT2A (0.38) | KMT2ANOTUMLMNAALDH1A1EPHX2 | |
| SCHEMBL8758725 | 0.74 | EPHX2 (0.51) | KMT2ALMNAALDH1A1EPHX2MEN1 | |
| SCHEMBL13293059 | 0.72 | KDM4E (0.51) | ALDH1A1EPHX2CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL11733493 | 0.72 | KMT2A (0.41) | KMT2ALMNAALDH1A1MEN1NPC1 | |
| SCHEMBL6249899 | 0.71 | KMT2A (0.46) | KMT2AALDH1A1 | |
| SCHEMBL12068514 | 0.71 | KMT2A (0.46) | KMT2AALDH1A1 | |
| SCHEMBL12066437 | 0.71 | ALDH1A1 (0.54) | LMNAALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099015-A | Antibiotics formed by bromination of trifluoromethanesulfonyl containing cephalosporins | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5013854-A | Process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1991-05-07 | — | — | US | disclosed |