⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482353 | 0.78 | — | — | |
| SCHEMBL13793633 | 0.76 | — | — | |
| SCHEMBL6235938 | 0.72 | CASP3 (0.31) | — | |
| SCHEMBL13789091 | 0.72 | — | — | |
| SCHEMBL2863306 | 0.67 | — | — | |
| SCHEMBL2813723 | 0.66 | — | — | |
| SCHEMBL11035106 | 0.64 | — | — | |
| SCHEMBL4164055 | 0.64 | — | — | |
| SCHEMBL10956062 | 0.62 | — | — | |
| SCHEMBL2502506 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323745-B1 | PHARMACEUTICAL PREPARATIONS | BEECHAM GROUP PLC (GB) | 1992-12-16 | — | — | EP | claimed |
| EP-0172352-B1 | ACTIVE BENZOPYRAN COMPOUNDS | BEECHAM GROUP PLC (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0076075-B1 | PHARMACEUTICALLY ACTIVE BENZOPYRAN COMPOUNDS | BEECHAM GROUP PLC (GB) | 1986-11-20 | — | — | EP | claimed |
| US-4555509-A | Anti-hypertensive benzo[b]pyran-3-ols | BEECHAM GROUP P.L.C. (GB) | 1985-11-26 | — | — | US | disclosed |
| US-4446113-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1984-05-01 | — | — | US | disclosed |