Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649368 | 0.82 | MAOB (0.69) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL9649398 | 0.82 | L3MBTL1 (0.73) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL27955195 | 0.80 | EGFR (0.71) | EGFRERBB2MEN1KMT2AGAA | |
| SCHEMBL9356235 | 0.79 | EGFR (1.00) | EGFRERBB2MMP2MMP9ERBB3 | |
| SCHEMBL23052404 | 0.79 | MEN1 (0.73) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL13680425 | 0.79 | EGFR (0.75) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL395608 | 0.79 | MEN1 (0.73) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL10361833 | 0.76 | MEN1 (0.69) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL13680429 | 0.76 | EGFR (0.71) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL2687295 | 0.76 | EGFR (0.78) | EGFRERBB2L3MBTL1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231835-B1 | ELECTRO PHOTOGRAPHIC RECORDING MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-4762760-A | FILM ON SUBSTRATE, ADHESION, FLEXIBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0231835-A2 | Electro photographic recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-12 | — | — | EP | disclosed |