Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612183 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2GLANR5A1ATMNPC1 | |
| SCHEMBL9650866 | 0.81 | NR5A1 (0.59) | SMN1; SMN2GLANR5A1ATMNPC1 | |
| SCHEMBL9650323 | 0.80 | NR5A1 (0.56) | NR5A1NPC1RAB9ATP53HPGD | |
| SCHEMBL9578566 | 0.77 | TP53 (0.63) | SMN1; SMN2NPC1RAB9ATP53HPGD | |
| SCHEMBL3785500 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2GLAATMNPC1RAB9A | |
| SCHEMBL17658992 | 0.77 | MRGPRX4 (0.40) | SMN1; SMN2GLANPC1RAB9AHPGD | |
| SCHEMBL8706961 | 0.76 | PLA2G4B (0.53) | NR5A1HPGDTSHRTHRATHRB | |
| SCHEMBL18998218 | 0.76 | KDM4E (0.45) | SMN1; SMN2GLANPC1RAB9AHPGD | |
| SCHEMBL9650226 | 0.76 | NPC1 (0.42) | NR5A1NPC1RAB9ATP53HPGD | |
| SCHEMBL15693373 | 0.75 | NR5A1 (0.65) | NR5A1NPC1RAB9ATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321984-B1 | MESOMORPHIC COMPOUND HAVING BETA-HYDROXYCARBOXYL GROUP AS CHIRAL SOURCE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4925591-A | FERROELECTRIC | MITSUBISHI RAYON CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0321984-A1 | Mesomorphic compound having beta-hydroxycarboxyl group as chiral source and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1989-06-28 | — | — | EP | disclosed |