Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15114753 | 0.84 | KDM4E (0.50) | MRGPRX4SLC6A4MEN1ALDH1A1KMT2A | |
| SCHEMBL3722908 | 0.83 | HRH3 (0.52) | HPGDNPC1RAB9ACYP2C19TDP1 | |
| SCHEMBL3720318 | 0.83 | LMNA (0.34) | MRGPRX4S1PR4MAPTL3MBTL1RAB9A | |
| SCHEMBL8751797 | 0.82 | HDAC8 (0.46) | MAPTCYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL6098978 | 0.82 | ALDH1A1 (0.50) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL6099804 | 0.82 | ALDH1A1 (0.46) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL6099486 | 0.82 | ALDH1A1 (0.50) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL6099784 | 0.82 | ALDH1A1 (0.46) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL4500324 | 0.81 | DRD2 (0.49) | MAPTHPGDNPC1RAB9ASLC6A4 | |
| SCHEMBL12800776 | 0.81 | MAPT (0.53) | MRGPRX4S1PR4MAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016051799-A1 | 2-AMINOHYDROQUINONE DERIVATIVE AND TAU AGGREGATION INHIBITOR | 学校法人同志社 | 2016-04-07 | — | — | WO | disclosed |