Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049604 | 0.79 | SLC5A2 (0.43) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| Thiobenzoic Acid SCHEMBL2049606 | 0.76 | TSHR (0.44) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| SCHEMBL28682859 | 0.74 | SLC5A1 (0.43) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| SCHEMBL11174010 | 0.74 | ALDH1A1 (0.43) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| SCHEMBL4452397 | 0.73 | SLC5A2 (0.42) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| SCHEMBL234078 | 0.73 | SLC5A1 (0.42) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| SCHEMBL31388216 | 0.73 | SLC5A2 (0.46) | TSHRSLC5A2SLC5A1ALDH1A1KEAP1 | |
| SCHEMBL15055774 | 0.71 | KMT2A (0.50) | TSHRALDH1A1HIF1ACYP2D6CYP2C19 | |
| SCHEMBL28357890 | 0.71 | TSHR (0.49) | TSHRSLC5A2SLC5A1CA1CA2 | |
| SCHEMBL1562120 | 0.70 | ALDH1A1 (0.59) | TSHRSLC5A2SLC5A1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243006-B1 | BLOCK-GRAFT COPOLYMERS AND PROCESS FOR PRODUCING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-4864003-A | Block-graft polymer and process for producing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| US-4803243-A | Block-graft copolymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0243006-A2 | Block-graft copolymers and process for producing the same | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |