⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650586 | 1.00 | — | — | |
| SCHEMBL11027486 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL8297540 | 0.60 | — | — | |
| SCHEMBL11116966 | 0.60 | — | — | |
| SCHEMBL22567098 | 0.59 | — | — | |
| SCHEMBL11879020 | 0.59 | CYP3A4 (0.34) | — | |
| SCHEMBL24263425 | 0.57 | — | — | |
| SCHEMBL10563056 | 0.56 | — | — | |
| SCHEMBL25363257 | 0.56 | — | — | |
| SCHEMBL10563065 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243924-B1 | 2-OXO-1-(SUBSTITUTED PHOSPHOROUS)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4723002-A | 1-(substituted phosphorous)-azetidinone antibacterials | E. R. SQUIBB & SONS, INC. | 1988-02-02 | — | — | US | disclosed |
| EP-0243924-A2 | 2-Oxo-1-(substituted phosphorous)azetidines | E.R. Squibb & Sons, Inc. (US) | 1987-11-04 | — | — | EP | disclosed |