Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363257 | 0.70 | — | — | |
| SCHEMBL10563056 | 0.70 | — | — | |
| SCHEMBL10563065 | 0.70 | — | — | |
| SCHEMBL8189717 | 0.69 | ACE (0.44) | CYP3A4TSHRTDP1MAPTAPEX1 | |
| SCHEMBL5656499 | 0.69 | ACE (0.44) | CYP3A4TSHRTDP1MAPTAPEX1 | |
| SCHEMBL9650586 | 0.68 | — | — | |
| SCHEMBL9650580 | 0.68 | — | — | |
| SCHEMBL22409043 | 0.65 | PIK3CD (0.48) | — | |
| SCHEMBL9739890 | 0.61 | POLB (0.36) | MAPT | |
| SCHEMBL1710152 | 0.57 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061765-B1 | BETA-LACTAMS | E.R. SQUIBB & SONS, INC. (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4478749-A | AMINO ACID DERTIVATIVES ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-23 | — | — | US | disclosed |