Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653233 | 0.99 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL9651887 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL9653285 | 0.84 | MAPT (0.46) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL9650733 | 0.84 | TDP1 (0.43) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL9653220 | 0.84 | MAPT (0.46) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL9652013 | 0.82 | TSHR (0.60) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL17261775 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL17261777 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 | |
| SCHEMBL9653905 | 0.81 | KMT2A (0.44) | SMN1; SMN2TDP1L3MBTL1POLBTHRB | |
| SCHEMBL2706971 | 0.78 | TDP1 (0.51) | SMN1; SMN2TSHRCASP1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213892-B1 | HERBICIDALLY ACTIVE ENOLS | ROHM AND HAAS COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0213892-A2 | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |