SCHEMBL9650880

SCHEMBL9650880

C[Si](C)(C)[Si](C)(C)CC#N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9649618 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL195841 0.72
SCHEMBL17732197 0.69
SCHEMBL29417588 0.67
SCHEMBL17550909 0.67
SCHEMBL12677773 0.67
SCHEMBL6525051 0.65 ALDH1A1 (0.32) ALDH1A1
SCHEMBL11204600 0.65
SCHEMBL11322789 0.61
SCHEMBL674489 0.58 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1290684-A None JP disclosed
US-5162559-A SILYLATION REAGENTS FOR PREPARING BINDERS WHICH ARE SOLUBLE IN AQUEOUS ALKALI AND CONTAIN SILANYL GROUPS IN THE SIDE CHAIN HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-10 US disclosed
JP-H01290684-A SILYLATION REACTANT FOR PRODUCING BINDER HOECHST AG 1989-11-22 JP disclosed
EP-0336276-A2 Silylation reagents for the preparation of binding agents soluble in aqueous alkyla and containing silanyl groups in the side chain HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed