Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 12/20 | 0.33 |
| ▸ | DRD2 | P14416 | 9/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648075 | 0.86 | GNAI3 (0.44) | GBA1 | |
| SCHEMBL9651134 | 0.86 | GNAI3 (0.44) | GBA1 | |
| SCHEMBL9648070 | 0.85 | — | — | |
| SCHEMBL9542986 | 0.78 | — | — | |
| SCHEMBL28482464 | 0.71 | GBA1 (0.41) | GBA1HTR1ADRD2CYP2D6TSHR | |
| SCHEMBL9649717 | 0.69 | DPP4 (0.30) | — | |
| SCHEMBL26640939 | 0.69 | — | — | |
| SCHEMBL19591929 | 0.68 | GBA1 (0.39) | GBA1HTR1ADRD2CYP2D6TSHR | |
| Alcohol SCHEMBL28265620 | 0.68 | GBA1 (0.32) | GBA1 | |
| SCHEMBL18501205 | 0.68 | GBA1 (0.39) | GBA1HTR1ADRD2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517225-A1 | Aminopyrrolidine platinum compounds, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1992-12-09 | — | — | EP | disclosed |