Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | AKT1 | P31749 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CDC25A | P30304 | 1/20 | 0.67 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651737 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL9649661 | 1.00 | LMNA (0.67) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL29613185 | 0.98 | LMNA (0.64) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL29613186 | 0.98 | LMNA (0.64) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL4972574 | 0.87 | LMNA (0.86) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL22568210 | 0.84 | LPAR3 (0.60) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL31577380 | 0.84 | SMN1; SMN2 (0.57) | LMNAAKT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23016878 | 0.82 | LMNA (0.82) | LMNAAKT1ESR1ADORA3CDC25A | |
| Elaidylphosphocholine SCHEMBL10415339 | 0.82 | LMNA (0.82) | LMNAAKT1ESR1ADORA3CDC25A | |
| Oleylphosphocholine SCHEMBL3332097 | 0.82 | LMNA (0.82) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292760-B1 | ORGANOPOLYSILOXANES CONTAINING A PHOSPHOLIPID-LIKE STRUCTURE AND A PROCESS FOR THEIR PREPARATION | TORAY SILICONE COMPANY, LIMITED (JP) | 1992-11-11 | — | — | EP | disclosed |
| EP-0292760-A2 | Organopolysiloxanes containing a phospholipid-like structure and a process for their preparation | TORAY SILICONE COMPANY, LIMITED (JP) | 1988-11-30 | — | — | EP | disclosed |