Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 4/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983114 | 1.00 | LMNA (0.48) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL6051342 | 0.89 | LMNA (0.61) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL31264442 | 0.89 | LMNA (0.61) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL6051333 | 0.89 | LMNA (0.61) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL9650999 | 0.88 | LMNA (0.48) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL8983006 | 0.88 | MAPT (0.51) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL8983012 | 0.88 | MAPT (0.51) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL9060569 | 0.87 | LMNA (0.50) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL9060577 | 0.87 | LMNA (0.50) | LMNAGAAMAPTPI4KBL3MBTL1 | |
| SCHEMBL8982981 | 0.86 | PI4KB (0.37) | LMNAGAAMAPTPI4KBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134138-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0409164-A2 | Phenacylpyridiniothiocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |