Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869098 | 0.87 | HPGD (0.37) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL10577820 | 0.86 | TSHR (0.50) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL13176704 | 0.86 | HPGD (0.41) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL24462646 | 0.83 | HPGD (0.39) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL16379922 | 0.83 | HPGD (0.39) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL17490271 | 0.81 | HPGD (0.44) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL5587483 | 0.81 | HPGD (0.44) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL1004841 | 0.80 | CYP3A4 (0.32) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL2050463 | 0.80 | HPGD (0.37) | HPGDTSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL11060919 | 0.80 | HPGD (0.37) | HPGDTSHRHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243869-B1 | PROCESS FOR THE PREPARATION OF DI-ORTHO-SUBSTITUTED DI-META-HALOGENATED PARA-HALOMETHYLPHENOLS | THE DOW CHEMICAL COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4740636-A | Di-ortho-substituted di-meta-halogenated para-halomethylphenols | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0243869-A2 | Process for the preparation of di-ortho-substituted di-meta-halogenated para-halomethylphenols | THE DOW CHEMICAL COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |
| US-4684752-A | HALOGENATION | THE DOW CHEMICAL COMPANY (US) | 1987-08-04 | — | — | US | disclosed |